Antineoplastic and Cytotoxic Evaluation of Green AgNPs and Crude Extracts from Agave americana, Mentha spicata, and Mangifera indica Leaves

Green silver nanoparticles (AgNPs) and crude ethanolic, methanolic, aqueous, acetonic extracts from leaves of Agave americana, Mentha spicata, Mangifera indica were scrutinized for possible antineoplastic cytotoxic efficacy. In this study, all the synthesized AgNPs characterized using UV-Vis spectroscopy, X-ray diffraction, SEM (scanning electron microscopy), TEM (transmission EDX-spectroscopy, simultaneous thermogravimetric differential thermal analysis (TG-DTA). Results various characterization analyses performed in study revealed that had highest absorption at 410-430 nm, polycrystalline structure with sizes ranging 23 to 38 thermally stable up 350°C. Furthermore, it was manifested phytoproduced A. americana good activity (69%). M. indica- spicata-based displayed moderate against PC-3 (prostate cancer cell line). Similarly, aptitude demonstrated by americana- indica-based sample concentration (1000 μL). Excellent cytotoxicity ethanol (100%), methanol aqueous (100%) extract (83%) spicata 1000 μL.